Mass Screening for Neuroblastoma in Miyagi Prefecture

MASAYUKI ITANO; SEI MORITA; HIROMI FUJIE; YOSHIYUKI OHASHI; NAOKO MINEGISHI; MASAYOSHI MINEGISHI; YOSHIKO YAMAGUCHI; TETSUO SATO; SHIGERU TSUCHIYA; TASUKE KONNO; YUTAKA HAYASHI; RYOJI OHI; HIROYUKI SHIRAISHI

doi:10.1620/tjem.168.137

MASAYUKI ITANO, SEI MORITA, HIROMI FUJIE, YOSHIYUKI OHASHI, NAOKO MINEGISHI, MASAYOSHI MINEGISHI, YOSHIKO YAMAGUCHI, TETSUO SATO, SHIGERU TSUCHIYA, TASUKE KONNO, YUTAKA HAYASHI, RYOJI OHI, HIROYUKI SHIRAISHI

Author information

MASAYUKI ITANO
Department of Pediatrics, The Research Institute for Tuberculosis and Cancer, Tohoku University
SEI MORITA
Department of Pediatrics, The Research Institute for Tuberculosis and Cancer, Tohoku University
HIROMI FUJIE
Department of Pediatrics, The Research Institute for Tuberculosis and Cancer, Tohoku University
YOSHIYUKI OHASHI
Department of Pediatrics, The Research Institute for Tuberculosis and Cancer, Tohoku University
NAOKO MINEGISHI
Department of Pediatrics, The Research Institute for Tuberculosis and Cancer, Tohoku University
MASAYOSHI MINEGISHI
Department of Pediatrics, The Research Institute for Tuberculosis and Cancer, Tohoku University
YOSHIKO YAMAGUCHI
Department of Pediatrics, The Research Institute for Tuberculosis and Cancer, Tohoku University
TETSUO SATO
Department of Pediatrics, The Research Institute for Tuberculosis and Cancer, Tohoku University
SHIGERU TSUCHIYA
Department of Pediatrics, The Research Institute for Tuberculosis and Cancer, Tohoku University
TASUKE KONNO
Department of Pediatrics, The Research Institute for Tuberculosis and Cancer, Tohoku University
YUTAKA HAYASHI
Department of Pediatric Surgery, Tohoku University School of Medicine
RYOJI OHI
Department of Pediatrics, The Research Institute for Tuberculosis and Cancer, Tohoku University
HIROYUKI SHIRAISHI
Miyagi Prefectural Center for Health Environment

JOURNAL FREE ACCESS

1992 Volume 168 Issue 2 Pages 137-139

DOI https://doi.org/10.1620/tjem.168.137

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Abstract

ITANO, M., MORITA, S., FUJIE, H., OHASHI, Y., MINEGISHI, N., MINEGISHI, M., YAMAGUCHI, Y., SATO, T., TSUCHIYA, S., KONNO, T., HAYASHI, Y., OHI, R. and SHIRAISHI, H. Mass Screening for Neuroblastoma in Miyagi Prefecture. Tohoku J. Exp. Med., 1992, 168 (2), 137-139 - In Japan, aiming at early and preclinical detection of neuroblastoma in infancy a mass screening program for the tumor has been implemented nationwide using urinary tests for catecholamine metabolites, vanillylmandelic acid (VMA) and homovanillic acid (HVA) (Sawada 1990; Sawada et al. 1991). In this report, the results obtained from the screening program in Miyagi Prefecture for the last 6 years are described. The detection rate of neuroblastoma by mass screening was 1:8, 377 among 125, 652 infants tested in Miyagi Prefecture. All but one patients survived after removal of the primary tumor and none or minimal chemotherapy. - neuroblastoma; mass screening; urine VMA; urine HVA

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