The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
On the Hypoglycaemic Action of Insulin upon Doubly Suprarenalectomized Rabbits
HYOZO TADA
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1931 Volume 17 Issue 5-6 Pages 588-598

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Abstract
Insulin was subcutaneously given to the rabbits, long surviving double suprarenalectomy, as 21 to 162 days, and the controls, in such dosage as to cause invariably convulsive attacks in the operated ones. The control experiment was ran simultaneously with that on the operated on.
While the convulsive attacks became manifest in nearly all the operated on, they failed to occur in some of the controls, a mere repetition of a well known fact.
Hypoglycaemia took place and in fact it developed usually much more rapidly in the operated ones than in the controls, but there was no material difference in the minimum percentage of the blood sugar achieved in both series of animals, decapsulated and non-operated.
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© Tohoku University Medical Press
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