1995 Volume 175 Issue 4 Pages 289-292
OKUYAMA, S. Antibiotic Pasting for Foul Putrefactive Cancers. Tohoku J. Exp. Med., 1995, 175 (4), 289-292 - Putrefaction of cancers is infrequent. Nonetheless, it presents a difficult clinical problem of foulness. We prepared 5% antibiotic pastes by adding sodium polyacrylate to aliquots of antibiotic solutions, and applied them to putrefactive lesions in 4 cases of rectal cancer, 2 of breast cancer and 1 of tongue cancer. The putrefaction was promptly brought under control in all of them, permitting an improved QOL. Concomitant application of anticancer pastes was also found remarkably effective. Use of sulperazone may offer a better chance of overcoming the β lactamase barrier in cases of prolonged use