Abstract
Starting from the fact that the lethal dosis of uranyl salt is very different according to different authors and that a certain relation is seen from a study of the literature between the liver and the kidney; I selected b- and f-classed rabbits according to the ammonia-detoxi-cating liver power (Cf. Sato-Sakurada's liver function test8)) and performed the experiment of uranyl nephritis. A subcutaneous injection of 0.1% uranyl acetate was made in an amount of 1.5 c. c. per kilo of body weight. The b-classed animals (of low-classed ammonia-de-toxicating liver power) succumbed without an exception, while, most of the f-classed rabbits (of high-classed liver power) outlived the poisoning excellently. This wide difference of susceptibility between both kinds of animals was also seen in the figures of blood urea. The same renal poison in the same amount reacted in a thus almost essentially different manner in rabbits of different liver power, _??_a very clear evidence of the close relation between the liver and the kidney.
