Abstract
To test the work capacity by means of a revolving wheel were directed normal rabbits, bilaterally suprarenalectomized, medullisuprarenalectomized or splanchnicotomized. The operated animals were indefinitely surviving and looked alert and had the body weight as the control animals.
Some animals in every set were unskillful in running in the revolving wheel, and they are omitted from consideration, as they are not properly qualified for this test.
The figures of the time needed for developing complete fatigue; the number of revolutions or the distance travelled, were practically wholly the same for the four sets of animals. That is, loss of the suprarenal glands, their medulla or the splanchnic nerves, has not material influence upon work capacity of rabbits.
However, there exists a definite difference between the normal animals and the doubly suprarenalectomized. The latter are apt to fall into convulsions, and some individuals died thereupon. The doubly medulli-suprarenalectomized rabbits showed also this ten-dency, though infrequently. Therefore those animals should betaken as possessing a small, but definite inferiority against detrimental ef-fect of severe exhaustion. Adrenaline hydrochloride showed some beneficial influence upon this detrimental condition.
