Abstract
0.1 grm. tyrosin, and 0.1 grin. or 0.5 grm. glycocoll were given intravenously into normal dogs and Eck fistula dogs.
Both amino acids were proved as producing similar response re the blood sugar concentration.
0.1 grm. tyrosin evoked almost no alteration in the blood sugar content in the normal dog, but in the Eck fistula dog a slight hyperglycaemia took place and was followed by a slight degree of hypoglycaemia.
0.1 grm. glycocoll induced in a normal dog no hyperglycaemia, but a long continued hypoglycaemia, but when applied to the dog pro-vided with the Eck fistula, a slight hyperglycaemia manifested itself before developing the hypoglycaemic period. And 0.5 grin. glycocoll evoked a slight but definite hyperglycaemia, followed by a small hypoglycaemia. The Eck fistula preparation apparently acts to prolong a little the hyperglycaemic period.
Briefly, establishment of the Eck fistula acts to elicit an increase in the blood sugar concentration on giving tyrosin or glycocoll. The hypoglycaemic effect of glycocoll will not be altered by that operation.
