The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
On the Influence of Drugs upon Intestinal Absorption
MASAKAZU NAKAMURA
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1924 Volume 5 Issue 1 Pages 29-46

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Abstract
Some drugs influence the intestinal absorption of various substances.
The effect differs with the kind of drug, i. e.
(1) Sodium fluoride, potassium cyanide, alcohol, zingerone, orexin, atropine and cocaine inhibit the absorption of water, sodium chloride, grapesugar, amino acid and fatty acids.
Among these the action of atropine is peculiar, i. e. the inhibiting action upon substances other than amino acid is not proper to atropine, but is only the consequence of its inhibition of amino acid.
(2) Carbonic acid gas and extractum gentianae scabrae promote the absorption of all these substances.
(3) Saponin, cantharidin, mustard oil, absinthin, columbin and caffeine, when smaller quantities of them are employed, promote the absorption of grapesugar and inhibit the absorption of the other substances. If larger quantities are employed, they seem to promote the absorption of amino acid also.
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© Tohoku University Medical Press
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