The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
The Blood Group Substance in Red Blood Cells
First Report. A Search for the Group (A, B, O)-Specific Substance in the Lipoid Fragment
Yutaka Hamasato
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1950 Volume 52 Issue 1-2 Pages 17-27

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Abstract
1. Strong group-specific lipoid-fractions were obtained from red blood cells.
2. From the physical and chemical properties of those fractions and for reasons by analogy the writer considered: a) the group lipoids from the present source contain galactose, sphingosine, nitrogen and phosphorus in the equivalent proportions of 1:1:3:2 in common, and the content of the sugar is nearly 16%; b) these active factors possess a solubility atypical of lipoids, namely, they give a complete solution in hot water and are difficultly soluble in such usual organic solvents as alcohol, ether, petroleum ether and acetone.
3. A “co-adsorbent” is present in erythrocytes. It resembles the group specific lipoids in composition (only qualitatively examined) as well as in solubility and promotes the sero-reaction of these.
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