Abstract
1. In human gastric mucosa besides peptic action, are found cathepsin action (pH 4.0-5.0, casein, egg albumin and serum albumin ) and catheptic _??_ pepton splitting action (cathopeptonase). And casein is also at pH 8.5 hydrolized (72 hrs.).
2. I have succeeded also with human gastric mucosa to separate the pepsin action from the cathepsin action, and also the cathopeptonase action from the erepsin action by means of acid and alkaline treatment respectively according to the methods of Utzino and Sakai.3)
3. In human gastric mucosa halogen-acylase action (pH 7.8, chlor-acetyl-1-leucin and chloracetyl-1-phenylalanin) is found, but carboxy-peptidase action (pH 7.8, benzoyl-diglycin, with kinase) or hippuricase action (pH 7.8, benzoyl-glycin) not. The hydrolysis of chlor-acetyl- _??_ diglycin at pH 7.8 by gastric mucosa from ulcer stomach is certain extent recognized.
4. Neither acid carboxy-peptidase action nor. acid acyldipeptidase action (pH 4.2-4.6, benzoyl-diglycin, chloracetyl-diglycin) despite of the cystein activation is still yet found. The hydrolysis of diglycin, chlor-acetyl-l-leucin, chloracetyl-phenylalnin and benzoyl-glycin at pH 4.5 with cystein, all of these are negative.
