1951 年 54 巻 3 号 p. 295-299
The present investigation was undertaken to know the methylene blue method is reliable or not for the estimation of adrenaline in the general blood.
The effect of adrenaline on the decolouration of methylene blue by muscle tissue had a large variation. Moreover we failed to find any evidence that the effect of serum of peripheral blood on the methylene blue decolouration is due to adrenaline. In fact, the effect of serum did not differ at all between that from the normal animals and those deprived of the suprarenals or totally sympathectomized.
Therefore the methylene blue method is not available for the estimation of adrenaline in the general blood.