1. The stimulation of the N. splanchnicus results in the temporary increase of the antibody-titer in the immunized dogs.
2. The peripheral blood and especially lymphocytes show marked quantitative and qualitative changes with the development of immuniza-tion as well as after the stimulation of the N. splanchnicus in the same im-munized animal.
3. After the interception of the venous blood flow from the adrenal gland by the ligation of the bilateral adrenal veins, the stimulation of the N. splanchnicus gives no significant effect to the antibody-titer and to the lymphocytes.
4. We discussed on the possible roles of the splanchnic nerve and anterior pituitary-adrenocortical system concerning the above-said find-ings.
