The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Specific Lytic Reaction of Bovine Erythrocytes Sensitized with Tuberculin, and Its Diagnostic Value upon Tuberculosis
Akira TakazawaKenichi KimuraKyuzo Omachi
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1953 Volume 57 Issue 4 Pages 299-309

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Abstract
1. The hemolytic reaction, using bovine erythrocytes sensitized with Dorset tuberculin, was examined in the sera of tuberculous and non, tuberculous peoples and the ordinary procedure was established.
2. Among the tested, 87 of 100 cases of tuberculous patients showed the positive results, while 13 of 90 cases of nontuberculous adults also gave a positive reaction. Among 90, non-tuberculous controls, 4 of 22 cases having no history of tuberculous, , 4 of 21 cases showing the positive tuberculin test and having tuberculous anamnesis in their past, 7 of 50 uses, having the positive tuberculin test without tuberculous anamnesisa and 1, in 19 cases having negative tuberculin test showed a positive reaction. The hemolytic, titers of such a non-tuberculous, adults, were much lower when compared with those of tuberculous, patients,
3. The relations between the degree of the hemolytic reaction and clinical symptoms, namely the stage of disease, the form of disease, the tuberculin reaction, the blood sedimentatipn rate and, the .number of tubercle bacilli in sputum, were discussed on 100 cases of tuberculous patients.
4. The hemolytic reaction is a specific one for tuberculosis, and seems to be so useful as a supplementary diagnostic method, of active tuberculosis.
The authors wish to express their hearty thanks to Prof. M., Kuroya and to Prof. T. Nakamura for their helpful advices and for their kind criticism.
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© Tohoku University Medical Press
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