The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Experimental Studies on Cardiac Resuscitation
I. Studies on the Restoration of the Heart Rhythm in Ventricular Fibrillation
堀内 藤吾
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1955 年 63 巻 1 号 p. 19-28

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Experimental study was carried out to observe the mechanism of return of cardiac rhythm after defibrillation of a fibrillating heart caused by electric stimuli, with following results:
1. Cardiac rhythm is restored by countershocks if applied within 3 minutes.
2. As hypercapnia increases, the irritability of cardiac muscle increases also. Ventricular fibrillation is hard to remove by countershocks and reccurs also easily after its removal.
3. As anoxia weakens the contractility of cardiac muscle, resusci-tation of the heart becomes difficult.
4. Ventricular fibrillation under hypothermia is difficult to remove by countershocks. Electric shock, however, seems to be the most ef-fective method for its abolition.

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