The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Experimental Studies on Cardiac Resuscitation
III. Studies on Disturbance of Cerebral Function Following Cardiac Arrest
堀内 藤吾
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1955 年 63 巻 1 号 p. 41-50

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Resuscitation of cardiac arrest was studied on the damage of cerebral function by EEG and histology.
1. The cerebral cortex has the least resisting ability to anoxia, and potentials of cerebral cortex disappear within 15 seconds after venticular fibrillation.
2. After ventricular fibrillation, the time limit to prevent irreversible damage of cerebral function is suspected to be 2 minutes.
3. If cardiac masage is started soon after ventricular fibrillation, no abnormal findings are recognized even when defibrillation is attempted after a long time.
4. In the case of cardiac arrest due to tracheal obstruction, it is possible to recover the heart without leaving permanent damage of cerebral function after release of the obstruction of the airway with restart of cardiac massage.

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