The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Relationships of the Predisposition to Convulsions with the Action Potentials of the Autonomic Nerves and the Brain
III. Changes in Action Potential of the Autonomic Nerves and the Brain under Conditions for Decreasing the Predisposition to Convulsions
大沼 倫彦
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1957 年 65 巻 2-3 号 p. 131-138

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1. With 10 rabbits and 4 cats it was demonstrated that the predis-position to convulsions were decreased by the following three conditions: barbiturate anesthetization, causation of ketosis, and bilateral thalamic destruction. Changes in action potential of the autonomic nerves and the brain under these conditions were examined.
2. There were observed no fundamental differences between the cat and the rabbit in action potential of the autonomic nerves and the brain, and the frequency histogram for each action potential had its peak in the range between 39.2 and 24 cycles per second in all cases.
3. Barbiturate anesthesia and ketosis brought about an increase of fast waves (39.2 cycles or more per second) in the action potentials of the vagus and the sympathetic, while thalamic destruction and barbiturate anesthesia caused a decrease in amplitude. It has been concluded that these predisposition-decreasing conditions act on both the vagus and the sympathetic in an inhibitory manner.
4. As for the brain potential, there was seen no definite tendency : Barbiturate anesthesia and thalamic destruction prolonged the period, while ketosis shortened it.

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