In rats pretreated with 2α-methyl-9α-chlorocortisol (Me-Cl-COL) and NaH2PO4, temporary occlusion of the pylorus regularly elicits acute, massive myocardial necroses and nephrocalcinosis, as well as a high mortality. The possible clinical implications of this fact, as regards the pathogenetic role of acute gastrointestinal disorders in the production of cardiac infarcts, is discussed.
About this Journal The Tohoku Journal of Experimental Medicine (TJEM) was founded in 1920
by professors of Tohoku Imperial University, Medical School.
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