抄録
On 51 cases of essential hypertension the relations between the clinical findings and the cerebral circulation and metabolism measured by N2O method have been investigated and the following facts elucidated:
1. With the advance of the retinal findings according to Keith-Wagener's classification, cerebral blood flow (CBF) and cerebral oxygen consumption (CMRO2) tend further to decrease and cerebral vascular resistance (CVR) to increase. The latter has a particularly close parallelism with the retinal findings.
2. In the group showing the hypertrophy of the left ventricle on the roentgenogram or the group, in which the left ventricular hypertrophy, coronary insufficiency or myocardial damage is suggested by the electrocardiographical findings, the disturbances in the cerebral circulation and metabolism are found the severer than in the groups without such finding. Similar relation in the group with prolonged circulation time may be confirmed.
3. No close parallelism is established between CBF and renal blood flow (RBF), while some correlation is found between CVR and renal vascular resistance (RVR), also, between the renal function, as tested with P. S. P. excretion, on the one hand and CBF and CVR on the other.
4. In the cases with lowered hemoglobin content of the blood, CBF is to some extent augmented.
