抄録
Although almost animals were induced by the administration of 40mg. per kg. body weight of alloxan, occurrence of diabetes mellitus by 30 mg.per kg. body weight of alloxan is the highest in the group of high-protein high-fat high-caloric diet among various dietary groups.
Progress of diabetes by alloxan administration was classified into three groups, namely persistent diabetization, recovery after diabetization and non-diabetization.
Furthermore it was emphasized that glucose tolerance was revealed to be decreased equally in the groups of recovery after diabetization and non-diabetization.
It was suggested that high-protein high-fat diet intensified the induc-tion of diabetes mellitus with the administration of small amount of alloxan and, therefore, could spare the amount of alloxan administered to induce experimental diabetes.
