Inhibitory Effect of Bile Constituents upon Bacterial β-Glucuronidase Activity

I. Effect of Normal Bile

Abstract

Using and assay system consisting of a bacterial β-glucuronidase preparation and phenolphthalein glucuronide, it was experimentally demonstrated that the bile, both the bladder bile and the choledochus bile, of patients without liver or biliary tract diseases had an inhibitory effect on the activity of bacterial β-glucuronidase.