Abstract
Some evidences suggesting an entity of proteolytic enzyme multiplicity in the euglobulin fraction were discussed from clinical and experimental observations.
1. The spontaneous caseinolytic activity was not always parallel with the spontaneous fibrinolysis in the euglobulin fraction. A marked fluctuation of the fibrinolytic activity during surgical operations with spinal anesthesia was noted; however, the changes of caseinolysis and TAMe-lysis were unremarkable. On the other hand, the caseinolysis in parturient women with postpartum hemorrhage fluctuated markedly, while the fibrinolysis and TAMe-lysis did not give any remarkable change.
2. There were 4 chromatographically different enzymes demonstrated in the euglobulin fraction on DEAE-cellulose column chromatography.
