抄録
A correlation between the juxtaglomerular apparatus, renin or angiotensin and aldosterone was studied in various diseases with special reference to hyper-tensive patients and cases of secondary aldosteronism. High juxtaglomerular cell count and increased aldosterone excretion or secretion were observed in cases of hypertension due to renal artery stenosis, progressed essential hypertension and secondary aldosteronism with edema or ascites. The results suggest strongly that renin secreted from the juxtaglomerular cells or angiotensin stimulates the adrenal cortex to secrete aldosterone. It is probable that the most important factor which activates this juxtaglomerular apparatus, renin or angiotensin and aldosterone system may be a decrease of circulating blood volume. Although the causality of this system to the incidence and the maintenance of hypertension is not clear, there is no evidence that this system plays a very important role.
