The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Assay of Anticoagulant Unit of ω-Heparin Newly Isolate from Whale's Lung and Intestine and its Toxicity
松野 正夫, 橋本 虎六
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1964 年 83 巻 2 号 p. 143-145

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Authors developed a modified assay method for standardization of anti-coagulant activity of whale heparin by use of the mixture of human and ox sulphated blood and ox thrombokinase. The stable unit was obtained by this method in the course of preservation of mixed sulphated blood at 4°C for 20 days. The toxicity of whale heparin was the same as that of beef heparin. Tests of the contamination of histamine and pyrogenic substance were negative.
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    The Tohoku Journal of Experimental Medicine (TJEM) was founded in 1920 by professors of Tohoku Imperial University, Medical School. The TJEM has been published continuously, except for the year of 1946 just after the World War II. The TJEM is open to original articles in all branches of medical sciences. The TJEM also covers the fields of disaster-prevention science, including earthquake archeology.


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