Abstract
The effect of follicle stimulating hormone (NIH-FSH-Sl), luteinizing hormone (NIH-LH-S1) and human chorionic gonadotrophin (HCG) on testicular 17-ketosteroid secretion in anesthetized dogs was investigated. The intravenous administration of FSH caused a slight rise in 17-ketosteroid secretion from the testis, the response being a transient nature. LH and HCG given intravenously provoked marked increases in the secretion, and the hypersecretion was sustained over at least a 2-4 hour observation period. Furthermore, the administration of FSH, with LH, effected a considerable potentiation of the 17-ketosteroid secretory response to LH.
