The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Folic Acid Clearance and Its Relation to Initial Levels of Serum Folic Acid Activity in Children
Keiichi HirataTsuneo Arakawa
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1965 Volume 87 Issue 3-4 Pages 249-258

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Abstract
Folic acid clearance curves, using both Lactobacillus casei and Streptococcus faecalis, following an intravenous injection of pteroylglutamic acid (PGA) (15γ per kg of bodyweight) was examined upon 29 children with various diseases. The result revealed that there was a close relation between the initial serum folate activity and the serum folate 240 minutes after the intravenous dose of PGA, and that there were 4 cases with abnormally high levels of serum folate before and after the intravenous injection of PGA.
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