The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Sympathetic Coronary Vasoconstriction after Adrenergic Beta Blockade
Kizuku Kuramoto, Kazuhiko Murata, Jun Fujii, Hiroshi Kurihara, Shin-ichi Kimata, Satoru Matsushita, Morio Kuramochi, Masao Ikeda, Kiku Nakao
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1967 年 91 巻 1 号 p. 95-101

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Sympathetic control of the coronary circulation was studied by eliminating the inotropic and chronotropic effects of sympathetic stimulation with adrenergic beta blockade. A remarkable vasoconstrictor effect of the left sympathetic nerve stimulation was observed after an intracoronary injection of propranolol, while the effect of the right sympathetic nerve stimulation was less prominent. The late increase in coronary flow after the cessation of the stimulation was observed to a lesser extent after the adrenergic beta blockade, while the blood pressure and heart rate remained unchanged. The sympathetic coronary vasoconstriction was almost abolished by adrenergic alpha blockade.
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    The Tohoku Journal of Experimental Medicine (TJEM) was founded in 1920 by professors of Tohoku Imperial University, Medical School. The TJEM has been published continuously, except for the year of 1946 just after the World War II. The TJEM is open to original articles in all branches of medical sciences. The TJEM also covers the fields of disaster-prevention science, including earthquake archeology.


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