Abstract
P-tosyl-l-arginine methyl ester hydrochloride (TAMe) esterase activity in human plasma was estimated on 30 healthy subjects and 130 patients with various diseases. In healthy subjects, TAMe esterase activities were 9-34μM/ml/hr with the mean value of 17. 8μM/ml/hr. Markedly low activities were observed in patients with carcinoma of the lung. In 9 out of 12 patients with carcinoma of the stom-ach, TAMe esterase activities were low.