抄録
1) A modification of Van Handel and Zilversmit's method was found to be suitable for routine clinical analysis of serum triglycerides because of its simplicity and sufficient accuracy.
2) The serum triglyceride levels in the fasting state of 263 normal subjects from 2 to 79 years of age were measured and examined in relation to age, sex and obesity.
a) The normal range of serum triglyceride levels was found to be 70±40mg% (mean±1.96 S. D.) with the mean of 70±1.3mg% (mean±S. E.). Therefore, the levels over 120mg% might be regarded as indicating hypertriglyceridemia.
b) The serum triglyceride levels of both sexes rose with increasing age and reached the maximum in the forties. Thereafter, the levels decreased with age. The mean levels were significantly different between every two successive age groups.
c) No significant sex difference was found with the exception of significantly higher triglyceride levels of females in the fifties and sixties. The levels of females were significantly higher after than before menopause.
d) Serum triglycerides tended to be higher in obese subjects than in subjects with normal body weight, and the lowest triglyceride levels were found in lean subjects. There was found a good positive correlation between relative body weight and serum triglycerides.
3) The serum triglyceride levels of 32 subjects of advanced ages over 90 years were also studied.
a) The mean triglyceride level of the subjects at 90 to 113 years of age had no significant difference as compared with that of the normal seventies.
b) Sex difference was not found in these aged subjects.