抄録
Titanium and its alloys have been widely used as biomaterials for hard tissue substitutes because of their good mechanical properties and biocompatibility. However, their osteointegration is less than bioactive ceramics. Therefore, various surface modification techniques have been developed to improve it. The purpose of the present work was to synthesis TiO2 and CaTiO3 films on pure Ti substrate by chemical/hydrothermal combined treatment and to investigate formability of hydroxyapatite (HAp) on the films. Pure Ti disks were chemically treated with H2O/HNO3 solutions at 353K for 20min to introduce an amorphous-like TiO2 layer on the surface. The specimens were then hydrothermally treated in an autoclave at 453K for 12h. Anatase-type TiO2 and perovskite-type CaTiO3 films with high crystallinity were obtained by the treatments with distilled water and Ca(OH)2 aqueous solution, respectively. Cracks in the amorphous-like TiO2 films were disappeared after the hydrothermal treatments; uniform and crack-free films could be obtained by the present process. Obtained samples were immersed in SBF (Simulated Body Fluid), which was adjusted at 310K. Precipitation of HAp on Ti was dimly observed after 6days immersion. On the TiO2 and CaTiO3 films, in contrast, it was obviously confirmed to precipitate after 2days.
