抄録
Dendron-type sugars with self-assembling properties were synthesized from conjugation of 2-azidoethoxylactose as hydrophilic block, dendron as divergent block, and 1-azidodocosane as hydrophobic block employing click chemistry for the each block. The dendron and 1-azidodocosane was coupled employing in the presence of copper sulfate and sodium ascorbate, followed by deprotection of tert-butyldimethylsilyl groups. Then, the deprotected alkyne and 2-azidoethoxylactose were condensed in the same catalyst to provide 2 and 4-divergent dendron-type sugars in good yield (up to 97%). The completion of the conjugation process was established by both 1H-NMR and ESI-MS spectroscopy. The interfacial Properties of dendron-type sugars were investigated by surface tension and dynamic light scattering measurements.
