Abstract
A 44-year-old man with diabetic ketoacidosis was treated with continuous subcutaneous insulin injection. On the fifth day, of hospitalization multiple red papules accompanied by severe pruritus, developed on the abdomen, face and extremities. The papules on the face and extremities disappeared leaving marked brownish pigmentation, as the patient's blood sugar level was controlled. Based on the specific clinical features and the histology of the lesions, a diagnosis of prurigo pigmentosa, was derermined. Prurigo pigmentosa is a rare inflammatory skin disease, that has been mainly reported in Japan. As there has been to date no report of prurigo pigmentosa associated with insulin-dependent diabetes mellitus, this case was considered very rare.
