1989 Volume 32 Issue 7 Pages 553-555
HLA-DR typing was performed in 25 Japanese patients with maturity-onset type diabetes of young people (MODY), 486 healthy randomly selected subjects and 94 patients with insulin-dependent diabetes mellitus (IDDM). No significant differences in HLA-DR were noted between Japanese MODY and healthy Japanese controls, which is exactly the same results observed among Caucasians. Compared with MODY and healthy Japanese controls, the frequency of DR 2 in IDDM patients was significantly decreased, while, the frequencies of DR4 and DR9 were significantly high. These finding suggest that HLA-DR types are not related to MODY.
