Journal of Toxicologic Pathology
Online ISSN : 1881-915X
Print ISSN : 0914-9198
ISSN-L : 0914-9198
Case Reports
Spontaneous Mucin-secreting Adenocarcinoma of the Ileum in a Male Crj: CD (SD) IGS Rat
Satoshi Furukawa, Koji Usuda, Kiyoshi Kobayashi, Yasuo Miyamoto, Kenichi Hayashi, Iwao Kaneko, Seiichi Ikeyama, Masanobu Goryo, Kosuke Okada
著者情報
キーワード: Ileum, Mucin-secreting adenocarcinoma, Osseous metaplasia, Rat, Spontaneous
ジャーナル フリー

2000 年 13 巻 1 号 p. 53-55

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A small intestinal mucin-secreting adenocarcinoma was found in a 78-week-old male Crj: CD (SD) IGS rat. The neoplasm was present in a portion of the ileum as a white soft mass. Histologically, it consisted of pleomorphic mucin-producing glands, multiple cysts of various sizes, and a well-developed dense fibrous tissue stroma. Chronic inflammatory reaction and osseous metaplasia were observed in the stroma. Ultrastructurally, the microvilli of the epithelium at the luminal surface contained core filaments, and often appeared more stubby and sparse than usual.
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© 2000 The Japanese Society of Toxicologic Pathology
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