Adenoma of the Nasal Submucosal Glands in the BDF₁ Mouse —One Case among 2000 Controls in 2-year Carcinogenicity Studies—

Abstract

A case of submucosal gland adenoma developed in the nasal cavity of a male BDF₁ mouse, 110 weeks of age, was presented. Histologically, a solitary nodule, 5 mm in diameter, showed an acinar structure resembling that of a serous gland. The present case was found in the posterior-most part of the nasal cavity, contrary to all previously reported, probably-induced, adenomas of the nasal cavity in mice, found in the anterior-most part of the nasal cavity.