Journal of Toxicologic Pathology
Online ISSN : 1881-915X
Print ISSN : 0914-9198
ISSN-L : 0914-9198

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Spontaneous T-cell lymphoblastic lymphoma in a young ICR mouse: a case report
Minkyoung SUNGJoo-Hee CHOISoo-Eun SUNGKyung-Ku KANGSun Hee PARKDuyeol KIMSijoon LEE
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ジャーナル オープンアクセス 早期公開

論文ID: 2024-0086

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Lymphoblastic lymphoma (LBL) is an aggressive neoplasm characterised by the proliferation of undifferentiated lymphocytes. It primarily spreads to immune organs such as the thymus, spleen, lymph nodes, bone marrow, and liver. Although well-documented in humans, spontaneous LBL cases in laboratory animals are exceedingly rare. This study reports a case of T cell-derived LBL in a young adult ICR mouse, notably without bone marrow metastasis. This case provides valuable insights into the spontaneous occurrence of LBL in laboratory rodents by contributing to comparative oncology and preclinical research.

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