The Health and Environmental Sciences Institute (HESI) is the global branch of the International Life Sciences Institute (ILSI) whose mission is to stimulate and support scientific research and educational programs that contribute to the identification and resolution of health and environmental issues of concern to the public, scientific community, government agencies, and industry. HESI’s programs bring together scientists from around the world from academia, industry, regulatory agencies, and other governmental institutions to address and reach consensus on scientific questions that have the potential to be resolved through creative application of intellectual and financial resources. This “tripartite” approach forms the core of every HESI scientific endeavor. As a non-profit organization, HESI provides a unique, objective forum for initiating dialogue among scientists with different perspectives and expertise. Industry members provide primary financial support for HESI programs, but HESI also receives financial and in-kind support from a variety of U.S. and international government agencies.