Host: The Japanese Society of Toxicology
Name : The 47th Annual Meeting of the Japanese Society of Toxicology
Date : 2020 -
Epigenetic modifications play an important role in gene transcription and are involved in numerous cellular processes. Two of the most characterized epigenetic modifications are DNA methylation and histone modification. Furthermore, the 3D-genome architecture has attracted much attention as an important epigenetic factor in gene regulation. My laboratory has been extensively analyzing their dynamic changes during early development of medaka fish using the quantitative ChIP-seq and HiC methods. In my talk, I will discuss the conservation and difference of epigenetic changes among vertebrate species and their roles in vertebrate development.
