Host: The Japanese Society of Toxicology
Name : The 50th Annual Meeting of the Japanese Society of Toxicology
Date : June 19, 2023 - June 21, 2023
To realize the new therapeutics and rescue patients who suffer incurable diseases, we set up comprehensive drug development system in our Kyoto University, under the strategy to maximize the serendipity for the academic drug discovery with open innovation. In our medical school, everybody can access to our original chemical libraries to screen compounds with own ideas using powerful cell-based assay machines in our Drug Discovery Center. If somebody succeeds to find out a hopeful small molecule, he/she can analyze the mode of action in Sections of Genetic Information Analysis, Mass Spectrometry, and Bio-imaging, synthesize structurally-developed compounds in MedChem Support Section, and further test the compounds in animal facilities. Then he/she can consult stuffs of Institute for Advancement of Clinical and Translational Science (iACT) to accomplish the non-clinical animal tests and prepare protocols of the clinical trial in Kyoto University Hospital. Using this system, we succeeded to develop several“Academia Drugs” in the fields of viral infections, cancers, and chronic pain. Even for genetic diseases such as Familial dysautonomia, EDA-ID (anhidrotic ectodermal dysplasia with immunodeficiency), cardiac Fabry disease, and type V cystic fibrosis, we found therapeutic small molecules.
