PFASの健康リスク

抄録

PFAS are some of the most prominent man-made chemicals in history due to their unique properties, such as water and oil repellence, chemical and physical resistance and surfactant nature, which cannot be reproduced by non-fluorinated hydrocarbons. PFAS comprise a wide variety of substances with carbon–fluorine (CF2) groups as a common molecular skeleton but exhibit structural differences including different chain lengths, moieties and branches. Due to their long-term and wide-range use, PFAS are found everywhere on the globe, even in environments far from human activities, such as the Arctic and Antarctic. There are increasing numbers of studies about the environmental fate and transport of PFAS, their toxicity to ecosystems, animals and humans and their effects on human society and economics. These studies have revealed the unique properties of PFAS, especially their long-range transport potential, environmental persistency and human health effects. Many alternatives have been introduced to the market with the aim of overcoming the problems associated with PFAS, but some of them have already been recognised as unsafe, i.e., regrettable substitution. In this presentation, the current evidence about PFAS health risks is summaries and discussed