Abstract
In young rats fed on a synthetic diet containing sucrose and pure crystals of every member of B-vitamins but thiamine, the typical syndrome of thiamine defficiency developed. The period of time required for the development of avitaminosis and the trend of change in body weight were almost the same as those found with the starch diet supplemented with some members of B-group, which authers used previously in many experiments. Even when some member or members of B-group were omitted from the sucrose diet mentioned above, the time for the development of thiamine avitaminosis and the change in body weight did not vary except when riboflavin was omitted.