Abstract
Young rats were kept on a riboflavin deficiency diet, and riboflavin content in several organs of these animals was examined weekly. The riboflavin content of the liver, heart and kidney was decreased to about 1/4-1/5 as much as that of the control 4 to 5 weeks after the onset of feeding, while that of spleen and adrenal glands was not decreased. When these riboflavin deficient rats were given either 40μg of riboflavin with irregular intermittence or given orally 80μg or 40μg of riboflavin daily, the riboflavin content of these organs was rapidly increased. The most remarkable increase was observed in the rats given 80μg of riboflavin daily.
