Abstract
In this report, it is studied histochemically on thetibiae in "phosphate cure" and in "vitamin D cure" of rickets. In the former, it can be observed the vigorous degeneration of cartilage matrix, but the invasion of bone marrow is far behind the advance of degeneration. In the latter, however, three changes : the degeneration of cartilage matrix, the invasion of bone marrow and the ossification are observed at the same region of metaphysis, and abundant osteoblasts appear in the primordial bone marrow. The alkaline phosphatase of metaphysis is seemed to have some relationship to the metabolism or degeneration of cartilage matrix.
