THE EFFECT OF N-CARBOBENZOXY-L-GLUTAMYLCHOLINE ON EXPERIMENTAL HYPERTENSION IN THE RABBIT

Abstract

The effect of N-carbobenzoxy-L-glutamylcholine on hypertension, experimentally induced in the rabbit by a cholesterol diet, was studied from the standpoint of hypotensive effect and histopathologically. An effect was noted both prophylactically and therapeutically in the blood pressure experiments. Histologically, there was an inhibition of atheroma development in the aorta and the deposition of fat in the various organs was less in the group given the compound prophylactically. It is suggested that there was a beneficial effect on fat metabolism.