Abstract
Measurement was made on the riboflavin content and the percentage of 3 forms of riboflavin in the organs of rats which were suffered from diabetes by administration of tryptophan-sodium lactate mixture, pyridoxal-deficient diet and alloxan injection. In the tryptophan-sodium lactate administrated rats, riboflavin content was decreased in liver, kidney and brain considerably, in heart slightly, and was unchanged in pancreas and muscle. In the pyridoxal-deficient rats, a decrease was observed in riboflavin content in liver, kidney, heart, pancreas, brain and muscle, marked in liver, kidney and heart. In the alloxan diabetic rats, riboflavin content was decreased remarkably in liver, kidney, heart, pancreas and muscle, but it was not decreased in brain. No considerble change was observed in the percentage of 3 forms of riboflavin in the organs of those rats.
