Abstract
The growth of Lactobacilli, usually used organisms for microbioassay, was completely inhibited by erythromycin in low concentrations such as 0.1〜0.5 μg/ml, but that of erythromycin resistant strain was not inhibited even by the presence of 1000 μg/ml of erythromycin. Evidence was presented indicating that erythromycin resistant Lactobacillus arabinosus 17-5 and Streptococcus faecalis R were available organisms for determination of pantothenic and folic acid respectively in the sample containing erythromycin, for example, in the urine which excreted after erythromycin doses.
