Abstract
As previously reported, the temperature have a remarkable influencnce for the riboflavin biosynthesis in the submerged culture of Ashbya gossypii In this paper, the experiments were performed whether any correlation exists between the riboflavin biosynthesis and cell growth. The influence of several growth inhibitors upon the growth and the riboflavin formation were examined. A remarkable increase of riboflavin production was found in a glucose medium containing 10^<-5>M of NaN_3. From the result obtained, it may be concluded that the stimulating effect of NaN_3 for riboflavin biosynthesis is concerned with the production or decomposition of 〜ph compound by the organism.
