Abstract
The authors examined histological changes, serum cholesterol contents, serum electrophoretic partition and lipemia clearing factor in arteriosclerotic patients and experimental atherosclerotic rabbits injected pyridoxal phosphate for long time. It was found that pyridoxal phosphate was able to prevent the arteriosclerotic changes. This seems to be due to the lypolytic factor of pyridoxal phosphate in the arterial wall with increase of serum albumin contents.