Abstract
It was revealed that the propylsulfide radical of TPD was separated immediately after TPD had passed to the tissues and it was soon absorbed independently of thiamine, and a part of it was excreted in the feces and urine through the lymphatic system. When TPD-^<35>S was given orally, 80 to 90 per cent of propylsulfide-^<35>S was excreted in the feces and urine, 41 hours later, while 50 to 60 per cent was excreted 48 hours after an intramuscular injection. Only 0.5 to 0.8 per cent was retainned in various organs (50 per cent of it was detected in the contents of the small intestine) 41 hours after an oral administration, and 3.3 to 4.5 per cent was retained in the organs (50 per cent was detected in the intestinal contents) 48 hours after an intramuscular injection.
