Abstract
Effects of pyrimidine nucleosides, uridine and cytidine (10 mg/kg/day), upon toxic fatty liver of rats induced by repeated administrations of CCl_4,controlling the decrease of phospholipid, choline esterase activity and iodine number of fatty acids in lipids, increase of neutral lipid and change of cholesterol ester ratio in liver, and thus reducing the fatty degeneration of liver, were observed. The mechanism of such actions will be discussed in the next paper in connection with the influences of these nucleosides upon other aspects of metabolism.
