Abstract
Column chromatography with Amberlite IRA-411 (OH^--form) was used to remove contaminations such as methionine or methionine sulfoxide which were active to the microbioassay of S-methylmethionine sulfonium chloride and the recovery of the latter through this treatment was excellent. Chemical assay of the latter compound which was based on ninhydrin color reaction was able to use for the determination of commercial preparations except those containing diastase, by using chromatographic treatment. Data between microbioassay and chemical assay were about the same.
