Abstract
Investigations were made on the clinical application of S-carbalkoxythiamine (CAT) to the 37 cases, picked up from the 405 out-patient cases of our clinic, by measuring the pyruvic acid level in blood. Dicarbethoxythiamine (DCET) being most absorbable among CAT group, was administered per os on the said cases and observations on the clinical appearance, the liver function and the pyruvic acid level in blood were made. As a result, a close relationship between the administration of DCET and the pyruvic acid level in blood was observed.